I notice that on:
http://www.engineeringchallenges.org/
....mastering self-replication didn't even get a mention.
A sign that people have grown scared about the possibility
of synthetic living systems, perhaps.
The nearest the list got to AI was "reverse-engineer the brain" -
probably one of the longest and least-likely routes to AI -
but often the one that gives humans the most warm fuzzy feelings.
The article spends a lot of time on "repairing broken brains",
and on applications involving human disability.
The list is dominated by health and ecology interventions.
The authors seem to be focussed on their wishlists, rather
than trying to imagine what is likely to be im****tant.
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